Asked by Emanuel Allison on Jun 25, 2024

verifed

Verified

Which type of genes, when abnormally activated, can result in cancer?

A) tumor suppressor genes
B) apoptosis initiator genes
C) proto-oncogenes
D) DNA repair protein genes
E) apoptosis executioner genes

Proto-oncogenes

Normal genes that can become oncogenes if mutated or expressed at high levels, potentially leading to cancer.

Tumor Suppressor Genes

Genes that help regulate cell growth and division, and can prevent the development of tumors by repairing DNA, promoting cell death, or ensuring cells do not proliferate uncontrollably.

Apoptosis Initiator

A molecule or signaling pathway that triggers the process of programmed cell death, crucial for development and maintaining homeostasis.

  • Delineate the genetic determinants of cell division, with an emphasis on the contributions of proto-oncogenes and tumor suppressor genes to cancer progression.
verifed

Verified Answer

LP
Leywes PierreJul 01, 2024
Final Answer :
C
Explanation :
Proto-oncogenes are normal genes that can become oncogenes when they are mutated or abnormally activated. Oncogenes promote cell growth and division, and when their activity is uncontrollably increased, they can lead to the development of cancer. Tumor suppressor genes, on the other hand, normally prevent cancer development by regulating cell growth and division, and mutations that inactivate tumor suppressor genes can also lead to cancer. However, the question specifically asks about genes that are abnormally activated, which is characteristic of proto-oncogenes. Apoptosis initiator and executioner genes regulate programmed cell death, which plays a role in cancer, but their abnormal activation is not directly linked to cancer development. DNA repair protein genes are involved in maintaining the integrity of the genome, and mutations in these genes can increase the risk of developing cancer, but their abnormal activation is not usually associated with cancer.