Asked by Chelsey Benoy on May 07, 2024

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What is the estimated odds ratio of cases when analyzing this study as a matched case-control study design? Use the information from a case-control study table. Exposure Status by Disease Status
 Pair no.  Cases  Controls 1 Exposed  Unexposed 2 Exposed  Exposed 3 Unexposed  Exposed 4 Exposed  Unexposed 5 Exposed  Unexposed 6 Unexposed  Exposed 7 Exposed  Exposed 8 Unexposed  Unexposed 9 Exposed  Unexposed 10 Unexposed  Unexposed 11 Exposed  Exposed 12 Unexposed  Exposed 13 Exposed  Unexposed 14 Enposed  Unexposed 15 Exposed  Eed \begin{array} { | l | l | l } \hline \text { Pair no. } & \text { Cases } & \text { Controls } \\\hline 1 & \text { Exposed } & \text { Unexposed } \\\hline 2 & \text { Exposed } & \text { Exposed } \\\hline 3 & \text { Unexposed } & \text { Exposed } \\\hline 4 & \text { Exposed } & \text { Unexposed } \\\hline 5 & \text { Exposed } & \text { Unexposed } \\\hline 6 & \text { Unexposed } & \text { Exposed } \\\hline 7 & \text { Exposed } & \text { Exposed } \\\hline 8 & \text { Unexposed } & \text { Unexposed } \\\hline 9 & \text { Exposed } & \text { Unexposed } \\\hline 10 & \text { Unexposed } & \text { Unexposed } \\\hline 11 & \text { Exposed } & \text { Exposed } \\\hline 12 & \text { Unexposed } & \text { Exposed } \\\hline 13 & \text { Exposed } & \text { Unexposed } \\\hline 14 & \text { Enposed } & \text { Unexposed } \\\hline 15 & \text { Exposed } & \text { Eed } \\\hline\end{array} Pair no. 123456789101112131415 Cases  Exposed  Exposed  Unexposed  Exposed  Exposed  Unexposed  Exposed  Unexposed  Exposed  Unexposed  Exposed  Unexposed  Exposed  Enposed  Exposed  Controls  Unexposed  Exposed  Exposed  Unexposed  Unexposed  Exposed  Exposed  Unexposed  Unexposed  Unexposed  Exposed  Exposed  Unexposed  Unexposed  Eed 

A) 0.50
B) 0.67
C) 1.00
D) 2.00
E) 2.25

Matched Case-Control

A study design where each case (individual with the outcome of interest) is paired with one or more controls (individuals without the outcome) who share similar characteristics, improving comparison.

Odds Ratio

is a measure of association between an exposure and an outcome, representing the odds that an outcome will occur given a particular exposure, compared to the odds of the outcome occurring without that exposure.

Exposure Status

The classification of individuals or groups in a study according to their level or type of exposure to a factor of interest, which may be related to disease outcomes.

  • Calculate and interpret odds ratios in unmatched and matched case-control study designs.
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MP
Markeno PorterMay 13, 2024
Final Answer :
D
Explanation :
The odds ratio (OR) in a matched case-control study is calculated by comparing the number of discordant pairs, i.e., pairs where one is exposed and the other is not. From the table: - Exposed cases with unexposed controls: 6 pairs (Pairs 1, 4, 5, 9, 13, 14) - Unexposed cases with exposed controls: 3 pairs (Pairs 3, 6, 12) The OR is the ratio of these, so OR = 6/3 = 2.00.