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Asked by Milanpreet kaur Chana on May 25, 2024

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Why can 1,2,2-trimethylaziridine be resolved into enantiomers while Why can 1,2,2-trimethylaziridine be resolved into enantiomers while cannot?
cannot?

Trimethylaziridine

A chemical compound characterized by a three-membered ring structure containing nitrogen and three methyl groups.

Enantiomers

Mirror-image molecules that are non-superimposable, differing in the spatial arrangement of atoms, commonly affecting their chemical behavior in a chiral environment.

  • Understand the principles and methods for resolving compounds into enantiomers.
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KT
Kierra TodmanMay 27, 2024
Final Answer :
In 1,2,2-trimethylaziridine the nitrogen atom is contained in a 3-membered ring and cannot readily achieve the sp2 transition state required for nitrogen inversion. Introduction of an sp2 center in a 3-membered ring greatly increases the angle strain.

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