Asked by Necko Clayton on May 07, 2024
Verified
Jared received a donor kidney. After the first week, it became apparent that Jared's body was rejecting the organ. This is due to
A) a lack of a match between Jared's immune cells and the MHC class I molecules on the cells of the donor kidney.
B) Jared's lack of helper T cells that prevent the lymphatic tissue of the donated kidney damaging the donated kidney.
C) an autoimmune disease that is destroying healthy tissue.
MHC Class I
Molecules found on the surface of all nucleated cells that present peptide fragments to the immune system, crucial for the recognition of self-cells by T cells.
Donor Kidney
A kidney that has been donated for transplantation, typically to replace a diseased kidney in a recipient.
Helper T Cells
A kind of T cell vital for the immune system as it activates and guides other immune cells.
- Acquire knowledge of the roles and functions performed by cells in adaptive immunity.
- Explain the unique characteristics of the immune response and how it targets distinct pathogens.
Verified Answer
GG
Glory GraceMay 12, 2024
Final Answer :
A
Explanation :
The rejection of a transplanted organ, such as a kidney, is often due to the recipient's immune system recognizing the donor organ as foreign. This is primarily because of a mismatch between the recipient's immune cells and the Major Histocompatibility Complex (MHC) class I molecules on the cells of the donor organ. The immune system sees these MHC molecules as foreign antigens and mounts an immune response against the organ.
Learning Objectives
- Acquire knowledge of the roles and functions performed by cells in adaptive immunity.
- Explain the unique characteristics of the immune response and how it targets distinct pathogens.