Which of the following is true about the neurotransmitters involved in schizophrenia?

A) Excess dopamine activity in the amygdala and unusually low dopamine activity in the frontal cortex play a role in schizophrenia.
B) Research suggests that the interaction between serotonin and dopamine are not critical in schizophrenia.
C) Research suggests that glutamate neurons do not affect brain activities of people with schizophrenia.
D) Excess dopamine activity in the mesolimbic pathway and unusually low dopamine activity in the prefrontal area play a role in schizophrenia.

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Daniel Mamane · Accepted Answer

Final Answer : D, Explanation :  Research suggests that excess dopamine activity in the mesolimbic pathway and unusually low dopamine activity in the prefrontal area play a significant role in schizophrenia. Serotonin and dopamine interactions are also believed to be important in schizophrenia, but not as critical as dopamine activity in these two pathways. Glutamate neurons have also been found to play a role in schizophrenia, with disruptions in the glutamate system leading to cognitive impairments.

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