Asked by Gianna Colella on Apr 27, 2024
Verified
Which of the following illustrates a violation to one of the assumptions made when using the Kaplan-Meier method?
A) Some patients who dropped out of the study have a similar probability of survival as those who remained in it.
B) Patients present the outcome at different time intervals.
C) An event of interest different from death is studied.
D) There is a significant improvement in the treatment of the condition being studied in the middle of the duration of the study.
E) The median survival time is longer than the duration of the study.
Kaplan-Meier Method
A statistical method used for estimating the survival rates of patients and the time until certain events, like death, occur.
Significant Improvement
A notable or considerable positive change in a condition or situation, often verified through statistical testing.
Probability of Survival
The statistical likelihood that an individual will continue to live for a certain period of time, often used in medical research.
- Recognize and explain the effects of violating assumptions in survival analysis.
Verified Answer
HG
Harveen GrewalApr 28, 2024
Final Answer :
D
Explanation :
A significant improvement in the treatment of the condition being studied is known as a secular (temporal) trend.One of the assumptions to use the Kaplan-Meier method is that no secular trends happen in the duration of the study.
Learning Objectives
- Recognize and explain the effects of violating assumptions in survival analysis.