Asked by Elizabeth Lezama on Jun 28, 2024
Verified
Which factor in a patient's medical history is most likely to prolong the half-life of certain drugs?
A) Heart disease
B) Liver disease
C) Rheumatoid arthritis
D) Tobacco use
Liver Disease
A broad category of conditions, illnesses, and disorders affecting the liver's functionality, including hepatitis and cirrhosis.
Half-Life
The time required for the concentration of a substance in the body to reduce to half its initial value, important in dosing medications.
- Identify the possibility of interactions between drugs and herbs and their effects on the efficacy of medications.
Verified Answer
MA
Md Ayaan ArbabJul 04, 2024
Final Answer :
B
Explanation :
Liver disease can impair the ability of the liver to metabolize drugs, which can lead to a prolonged half-life of certain drugs. The liver is responsible for breaking down drugs and eliminating them from the body, so if it is not functioning properly, drugs may stay in the body longer and accumulate to toxic levels. Heart disease, rheumatoid arthritis, and tobacco use may affect drug metabolism and clearance in different ways but they are not typically associated with a prolonged half-life of drugs.
Learning Objectives
- Identify the possibility of interactions between drugs and herbs and their effects on the efficacy of medications.