What was Hildegard Peplau's major contribution to nursing?

A) Transcultural nursing
B) Health promotion
C) Nurse-patient relationship
D) Holistic comfort

Hildegard Peplau's major contribution to nursing is the development of the nurse-patient relationship theory. Her theory focuses on the therapeutic relationship between the nurse and patient, and the role of the nurse in promoting the patient's mental health and well-being. Peplau emphasized the importance of communication, empathy, and trust in this relationship, and her theory has had a significant impact on nursing practice and education.