Asked by Destiny Walker on Apr 27, 2024

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What is the disadvantage of polymyxin B as an antibiotic?

A) It can act as a neurotoxin.
B) It is not always effective against bacteria.
C) It is not effective at physiological pH.
D) Nothing; it is an excellent antibiotic.

Polymyxin B

An antibiotic used to treat bacterial infections by disrupting the cell membrane, primarily active against Gram-negative bacteria.

Neurotoxin

A toxin that specifically targets neural tissues, potentially causing damage to the nervous system, which includes both central and peripheral components.

Physiological pH

The specific value of pH (around 7.4) within biological systems where the internal environment is regulated to maintain stable and optimal conditions for cellular processes.

  • Understand the mechanism of action of antibiotics and their limitations.
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ZK
Zybrea KnightMay 04, 2024
Final Answer :
A
Explanation :
Polymyxin B can act as a neurotoxin, which is a significant disadvantage. This can lead to neurotoxic effects, such as neurotoxicity, when used as an antibiotic.