What is a characteristic of total androgen insensitivity syndrome?

A) No testosterone is produced.
B) Chemicals circulating in the blood deactivate testosterone.
C) The cellular receptor for testosterone in the target cells is defective.
D) Affected individuals are phenotypically male, but are sterile.
E) Testosterone is degraded quickly.

Total androgen insensitivity syndrome is a X-linked recessive disorder in which the cellular receptor for testosterone in the target cells is defective, leading to the inability of androgens to exert their effects. Affected individuals have a male genotype (XY), but a female phenotype due to the lack of virilization during development. They have minimal to no pubic and axillary hair, are infertile and have testes that remain in the abdomen or inguinal canal. Testosterone production is normal or elevated and there is no deactivation or rapid degradation of testosterone.