What happens to an operant response,in order to extinguish that response

A)  It is followed by intermittent reinforcement. 
B)  It is no longer associated with the CS. 
C)  It is no longer followed by reinforcement. 
D)  It is followed by continuous punishment

In order to extinguish an operant response, it must no longer be followed by reinforcement. This means that the behavior is no longer rewarded or reinforced, leading to a decrease in the frequency of the operant response. Continuous punishment may suppress the behavior temporarily, but it does not lead to the extinction of the response. Intermittent reinforcement can actually strengthen the behavior, so it is not effective in extinguishing the response. The association with a conditioned stimulus (CS) is relevant to classical conditioning, not operant conditioning.