The term holophrase is used to denote:

A) a word that is empty of meaning.
B) the infant's use of one word to express a whole thought.
C) the relationship of object permanence to language development.
D) the use of two words to take the place of one.

A holophrase refers to an infant's use of a single word to express a complete thought or idea. This typically develops in the early stages of language development, where a child may say "mama" to indicate "I want to see my mother" or "food" to indicate "I'm hungry." It is not related to object permanence or the use of two words to replace one.