The side effects of neuroleptics can be reduced:

A) through prolonged usage.
B) by reducing dosages.
C) by using them in combination with over-the-counter drugs.
D) by taking the drugs at intervals.

The side effects of neuroleptics can be reduced by reducing dosages. Prolonged usage, using them in combination with over-the-counter drugs, or taking the drugs at intervals do not necessarily reduce side effects, and could actually lead to more side effects or other complications.