Asked by Terrence Phelps on May 12, 2024

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The nurse recognizes that patients with which conditions will have a reduction in the distribution of drugs? (Select all that apply. )

A) Peripheral vascular disease
B) Heart failure
C) Liver disease
D) Obesity

Peripheral Vascular Disease

A vascular disorder in which blood vessels outside the heart and brain are constricted, frequently resulting in diminished blood circulation to the extremities.

Heart Failure

Heart failure is a chronic condition where the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs.

Distribution of Drugs

The process of delivering medications to patients or healthcare facilities following legal and logistical practices.

  • Identify the correlation between the pharmacokinetics processes (absorption, distribution, metabolism, excretion) and patient states, including liver disease.
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TT
Tamra TiltonMay 17, 2024
Final Answer :
A,B
Explanation :
The rate and extent of distribution depend on circulation,cell membrane permeability,and protein binding.Peripheral vascular disease and heart failure result in a decrease in circulation,which reduces distribution.Liver disease causes a reduction in plasma proteins,which results in more free active drug that is distributed more readily.Obesity does not affect distribution.