The diathesis-stress model has been proposed as a model of development of schizophrenia. Choose three factors that play a role in vulnerability to schizophrenia and describe the research findings.

(Factors include: developmental influences, genetic factors, biochemical influences, neuroanatomical factors, prenatal and perinatal influences, neurodevelopmental factors, and personality factors).
The vulnerability-stress perspective suggests that certain individuals are vulnerable to schizophrenia, and these people develop symptoms after being exposed to certain stressors. Many different factors are believed to increase vulnerability, for example, developmental influences, genetic factors, and biochemical influences.
High-risk studies, in which the subjects are children of mothers with schizophrenia, are used to examine developmental influences in the etiology of schizophrenia. Reviews of high-risk studies have found few differences between high- and low-risk children that specifically predict schizophrenia, although high-risk children tend to have more difficulty with attention tasks and those who later developed schizophrenia tend to have poor neuromotor test scores.
Genetic factors appear to play an important role in the development of schizophrenia, however, research is difficult because the gene(s) responsible for schizophrenia has (have) reduced penetrance (certain environmental factors are required in order for the person to develop symptoms). One method of determining the role of genetics is through concordance rates within families. Studies have shown that only around 10% of people who have a parent with schizophrenia end up developing the disorder, and 90% of people who do develop schizophrenia have a first-degree relative with schizophrenia. The concordance rate for identical twins is less than 50%, indicating that genetic factors are not the only ones involved. One marker for schizophrenia that has received much attention is eye-tracking dysfunction. The eye movements of people with schizophrenia are less efficient and more erratic than those without the disorder. However, not everyone who develops schizophrenia displays these impairments.
Neurotransmitters, particularly dopamine, have received attention in the schizophrenia research. People with schizophrenia are believed to have either too many or too sensitive dopamine receptors, for several reasons. Firstly, the neuroleptic medications used to reduce the hallucinations and delusions in schizophrenia work by blocking the transmission of dopamine. Secondly, the density of dopamine receptors is greater in certain areas of the brain among those with schizophrenia. Recent evidence suggests thatglutamate may play a role in the development of the disorder, as may other neurotransmitters. The role of various neurotransmitters in the etiology of schizophrenia appears to be complex. One issue is that changes or abnormalities in receptors for example may be the cause of schizophrenia, or may results from prolonged use of anti-psychotic medications.