Genetically, a female is defined as a person who has ________ chromosomes and a male is defined as one who has ________ chromosome.

A) two Y; an X and a Y
B) two X; more than one Y
C) sex; a gender
D) two X; an X and a Y

A female has two X chromosomes while a male has one X chromosome and one Y chromosome. Therefore, option D is the correct answer. Options A and B are incorrect as having two Y chromosomes is not possible in humans and having more than one Y chromosome would lead to genetic abnormalities. Option C is also incorrect as sex and gender are different concepts - sex refers to biological characteristics while gender refers to social and cultural roles and expectations.