Enzymes called ____ form breaks in the DNA molecules to prevent the formation of knots in the DNA helix during replication.

A) topoisomerases
B) single-strand binding proteins
C) DNA polymerases
D) RNA polymerases
E) DNA ligases

Topoisomerases

Enzymes that relieve twists and kinks in a DNA molecule by breaking and rejoining the strands.

DNA Molecules

The carriers of genetic information in living organisms, consisting of two long chains of nucleotides twisted into a double helix.

Replication

To provide a 3' end to which DNA polymerase adds nucleotides. The RNA primer is later degraded and replaced with DNA.