Distamycin and derivatives have exhibited antiviral, antibiotic, and antitumor activity by binding to the minor groove of DNA (J. Med. Chem. 2004, 2133). Place a line through each bond of distamycin that would be cleaved by acid hydrolysis.

Distamycin

A small molecule that binds to minor grooves of DNA, notable for its role in scientific research related to DNA interactions.

Acid Hydrolysis

A chemical process in which a compound is broken down by reaction with water and an acid, resulting in the formation of one or more new substances.

Minor Groove

A narrower space between two strands of a DNA helix, distinguished from the major groove by its size, and specific for protein binding and DNA interactions.