Describe how cells regulate the conversion of glucose-6-phosphate to fructose-1,6-bisphosphate as catalyzed by phosphofructokinase (PFK) and how this mechanism mediates the process of aerobic respiration.

Phosphofructokinase (PFK)

An important enzyme in the glycolytic pathway, regulating the rate of glucose breakdown by converting fructose-6-phosphate into fructose-1,6-bisphosphate.

Glucose-6-phosphate

A glucose sugar phosphorylated at the 6th carbon, playing a critical role in energy metabolism and the glycogen storage pathway.

Fructose-1,6-bisphosphate

A fructose sugar phosphorylated on carbons 1 and 6, an important intermediate in glycolysis which breaks down sugar for energy production in cells.