Decisions concerning the role of each facility are significant because they determine the amount of flexibility the supply chain has in changing the way it meets demand.

The statement is true, as the role of each facility in the supply chain can affect the ability to respond to changes in demand and adjust production or distribution accordingly. Different facilities may have different capacities, capabilities, and costs, which may impact the efficiency and effectiveness of the supply chain as a whole. For example, if a facility is designed for high-volume production but low flexibility, it may be less able to adapt to shifts in customer preferences or market conditions than a facility that is more agile and adaptable. Therefore, it is important to make informed decisions about the role of each facility in the supply chain to optimize performance and minimize risks.