Chronic stress may lead directly to cardiovascular disease because of the repeated release of which of the following?

A) Histamine
B) Catecholamines
C) Cortisol
D) Protease

Catecholamines

Chemical compounds, including epinephrine and norepinephrine, which are produced by the adrenal glands and function as neurotransmitters and hormones, playing key roles in the body's response to stress.

Cortisol

A steroid hormone produced by the adrenal glands, often released in response to stress and low blood-glucose concentration.

Histamine

A nitrogenous compound involved in local immune responses, regulating physiological function in the gut, and acting as a neurotransmitter for the brain, spinal cord, and uterus.