Asked by Audrey Sarver on May 22, 2024
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Acetyl groups attached to histone tails generally indicate that the genes associated with this nucleosome will be transcriptionally inactive.
Acetyl Groups
Functional groups derived from acetic acid, consisting of a methyl group single-bonded to a carbonyl. The formula is CH3CO, often denoted as Ac in chemical structures.
Histone Tails
Histone tails are the N-terminal extensions of histone proteins that protrude from the nucleosome and play a key role in regulating gene expression by undergoing various chemical modifications.
Nucleosome
A basic unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound around a core of histone proteins.
- Understand the concepts of epigenetics and their role in gene expression.
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Learning Objectives
- Understand the concepts of epigenetics and their role in gene expression.
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