Asked by Karen Figueroa on Jun 19, 2024
Verified
A mutation in the IGF2 gene in pigs results in a threefold increase in the transcriptional activity of this gene in muscle cells; therefore, these pigs are leaner and more muscular. Because this mutation is in the noncoding region of the IGF2 gene, we can infer that:
A) the IGF2 gene is a prokaryotic gene.
B) the IGF2 gene is present only in muscle cells but not in adipose (fat) cells.
C) the mutation changes the amino acid sequence of the IGF2 protein.
D) the mutation alters the regulatory region of the IGF2 gene.
E) less IGF2 protein is synthesized in the muscle cells of these pigs.
Transcriptional Activity
The process of copying a segment of DNA into RNA by the enzyme RNA polymerase, crucial in gene expression.
Noncoding Region
Sections of DNA that do not code for proteins but may have regulatory roles in gene expression, chromatin structure, and genome organization.
IGF2 Gene
A gene that encodes the insulin-like growth factor 2, playing a crucial role in growth and development, especially fetal growth.
- Comprehend the role of regulatory regions and proteins in gene expression and how mutations can affect gene function.
Verified Answer
MS
Milena StuparJun 20, 2024
Final Answer :
D
Explanation :
The mutation being in the noncoding region and affecting transcriptional activity suggests it alters the regulatory region of the IGF2 gene, which controls when, where, and how much gene product is made, rather than changing the protein's structure or amount directly.
Learning Objectives
- Comprehend the role of regulatory regions and proteins in gene expression and how mutations can affect gene function.